Fmoc-Gly-Gly-OH

Fmoc-Gly-Gly-OH

Isicelo soPhando:
I-Fmoc-Gly-Gly-OH yidipeptide esetyenziswa njengebhloko yokwakha esisiseko kwi-soli-phase peptide synthesis (SPPS). Ibonisa iintsalela ze-glycine ezimbini kunye ne-Fmoc-ekhuselweyo ye-N-terminus, evumela ukulawulwa kwekhonkco le-peptide. Ngenxa yobungakanani obuncinci be-glycine kunye nokuguquguquka, le dipeptide ihlala ifundwa kumxholo we-peptide backbone dynamics, uyilo lwekhonkco, kunye nemodeli yesakhiwo kwiipeptide kunye neeproteni.

Umsebenzi:
I-Fmoc-Gly-Gly-OH ibonelela ngecandelo eliguquguqukayo kunye nelingahlawuliswanga ngaphakathi kokulandelelana kwepeptide. Iintsalela ze-Glycine zazisa inkululeko ehambelanayo, zenza le dipeptide ibe yelungele ikhonkco, ujiko, okanye imimandla engamiselwanga kwiipeptides ezisebenzayo. Isetyenziswa ngokubanzi kuyilo lweepeptides ze-bioactive, i-enzyme substrates, kunye ne-bioconjugates apho isithintelo esincinci se-steric kunye nokuguquguquka kufunwa.