Ngo-2025, iTirzepatide ifumana ukukhula okukhawulezayo kwicandelo lonyango lwezifo ze-metabolic. Ngokutyeba ngokugqithisileyo kunye nokuxhaphaka kwesifo seswekile okuqhubeka nokunyuka, kunye nokwandisa ulwazi loluntu ngolawulo olupheleleyo lwe-metabolic, le GLP-1 yesenzo se-GLP-1 kunye ne-agonist ye-GIP yandisa ngokukhawuleza indawo yayo yentengiso.
U-Eli Lilly, kunye neempawu zayo i-Mounjaro kunye ne-Zepbound, ubambe isikhundla esiphezulu kwihlabathi. Ukuxhaswa bubungqina obuqinileyo bekliniki, ukuphumelela kweTirzepatide ekulawuleni i-glycemic, ukulahleka kwesisindo, kunye nokukhuselwa kwentliziyo kuye kwaqinisekiswa ngakumbi. Idatha yamva nje yekliniki ka-2025 ibonisa ukuba i-Tirzepatide iwagqitha amachiza afanayo ekwehliseni umngcipheko omkhulu wesiganeko sentliziyo, ngokuncipha okuphindwe kabini kokusweleka. Le mpumelelo ayikhulisi nje ukuzithemba kukagqirha kodwa komeleza imeko yothethathethwano ngembuyekezo efanelekileyo.
Uphuhliso lomgaqo-nkqubo lukwafaka amandla ekukhuleni kwemarike. Urhulumente wase-US ubhengeze izicwangciso zokubandakanya iziyobisi zokunciphisa umzimba, kuquka i-Tirzepatide, phantsi kwe-Medicare kunye ne-Medicaid coverage eqala ngo-2026. Oku kuya kwandisa kakhulu ukufikelela kwezigulane, ngokukodwa phakathi kwabantu abangabizi kakhulu, ukukhawuleza ukungena kwiimarike. Ngeli xesha, ummandla we-Asia-Pacific uvela njengeyona ndawo ikhula ngokukhawuleza yentengiso ngenxa yohlaziyo lwezempilo, i-inshurensi ebanzi, kunye nesiseko sayo esikhulu sabantu.
Nangona kunjalo, imingeni isekhona. Ixabiso eliphezulu le-Tirzepatide—elihlala lidlula i-$1,000 ngenyanga—liyaqhubeka linciphisa ukwamkelwa komntwana wabanye abantu abaninzi apho i-inshorensi inganelanga. Izithintelo zasemva kokunqongophala kwe-FDA kwiigenerics ezidityanisiweyo nazo zonyuse iindleko kwezinye izigulana, okukhokelela ekuyekisweni konyango. Ukongeza, iziphumo ebezingalindelekanga ezixhaphakileyo zesisu esiswini ezinxulumene namachiza e-GLP-1, kunye neenkxalabo zolawulo kwiitshaneli zokuthengisa ezikwi-Intanethi, zifuna uqwalaselo oluqhubekayo kuwo omabini amashishini kunye nabalawuli.
Ukujonga phambili, ukukhula kwemarike yeTirzepatide kuhlala kukhulu. Ngokwandiswa okungaphaya (umzekelo, i-apnea ephazamisayo yokulala, uthintelo lwesifo sentliziyo), ukhuseleko lwe-inshurensi enzulu, kunye nokwamkelwa kwezixhobo zolawulo lonyango lwedijithali kunye neenkqubo zenkxaso yezigulana, isabelo sikaTirzepatide kwimakethi yehlabathi yamachiza e-metabolic kulindeleke ukuba inyuke ngokuthe chu. Kubadlali beshishini, ukuxhamla kwizibonelelo zeklinikhi, ukukhulisa iimodeli zentlawulo, kunye nokuqinisekisa ukubakho kwangethuba kwiimarike ezikhulayo kuya kuba ngundoqo ekuphumeleleni ukhuphiswano lwexesha elizayo.
Ixesha lokuposa: Aug-05-2025