I-GH / I-IGF-1 iyancipha ngokwasemzimbeni, kwaye ezi nguqu zihamba kunye nokudinwa, i-atrophy yemisipha, inyuka i-tishu, kunye nokonakala kwengqondo kwabadala ...
Ngo-1990, uRudman wapapasha iphepha kwi-England New Journal yamayeza othuse uluntu - "ukusetyenziswa kwe-hormone yokukhula kwabantu kubantu abangaphezu kwama-60 ubudala. URudman ukhokela amadoda ali-12 ubudala i-61-81 yovavanyo lweklinikhi:
Emva kweenyanga ezi-6 zenaliti, izifundo zazinokonyuka kwe-8.8% kwimisipha yezihlunu, i-14,4% kwi-Stone Dolling, i-19% kwiqela labantu abadala abakhonzana nabanye abantu abalupheleyo beminyaka eninzi. %, kwagqitywa kwelokuba utshintsho lwembali kuzo zonke izifundo ngeminyaka eli-10 ukuya kwengama-20 ubudala.
Esi sigqibo sikhokelele ekukhuthazeni okubanzi kwe-hormone ephindaphindwayo (i-RHGH) njengesiyobisi esincinci, kwaye ikwangunobangela wenkozo yabantu abaninzi ukuba inaliti ye-RHGH ingaluthando. Ukususela ngoko, abantu basekliniki abaninzi basebenzise i-HGH njengechiza elichasene ne-aning, nangona bengavunywa yi-FDA.
Nangona kunjalo, njengoko uphando luyaqhubeka ukhula, izazinzulu zifumanise ukuba izibonelelo ezincinci kumzimba wokwandisa umsebenzi we-GH / 1 Axis AKUKHO BUNGOZI NGOKUGQIBELA KWABADALA, KUKHONA KUKHONA IMIHLA YOKUZIPHATHA:
Iimpuku zigqogqo i-GH zinkulu, kodwa zineepesenti ezingama-30 zokuphila ezimfutshane kunemida ye-gesi [2], kunye notshintsho lwe-hepatophelols kunye ne-hepatocyte proliferasis) yenzeka kwiimpuku eziphezulu ze-GH. enkulu) kunye nokunganyangeki kwe-insulin.
Amanqanaba aphezulu e-GH akhupha ukukhula kwezihlunu, amathambo, kunye nezigaba zangaphakathi, okhokelela kwi-gigantism (ebantwaneni) kunye ne-aramegaly (kubantu abadala). Abantu abadala abane-GH GHH bahlala bedityaniswa nesifo seswekile kunye neengxaki zentliziyo, kunye nomngcipheko ophezulu womhlaza.
I-Post Ixesha: IJUL-22-2022