I-Retatrutide lichiza eliphambili lophando elimele isizukulwana esitsha solawulo lobunzima kunye nonyango lwe-metabolic. Ngokungafani namayeza esintu ajolise kwindlela enye, i-Retatrutide yi-agonist yokuqala emithathu eyenza i-GIP (i-glucose-exhomekeke kwi-insulinotropic polypeptide), i-GLP-1 (i-glucagon-like peptide-1), kunye ne-glucagon receptors ngaxeshanye. Le ndlela ikhethekileyo yenza ukuba ikwazi ukuhambisa iziphumo ezinzulu ekulahlekeni kobunzima, ulawulo lwe-glucose yegazi, kunye nempilo ye-metabolic.
Isebenza njani iRetatrutide
1. Yenza i-GIP Receptors isebenze
- Yandisa ukukhuselwa kwe-insulin ekuphenduleni ukutya.
- Ukuphucula ukusebenza kakuhle kwe-metabolic kunye nokusetyenziswa kwamandla.
- Idlala indima ngokuthe ngqo ekunciphiseni ukuqokelelwa kwamafutha kunye nokuphucula ukuvakalelwa kwe-insulin.
2. Ivuselela i-GLP-1 Receptors
- Yehlisa ukuphuma kwesisu, ikunceda uhlale ugcwele ixesha elide.
- Ukunciphisa ukutya kunye nokunciphisa ukuthathwa kwekhalori ngokubanzi.
- Ukuphucula ulawulo lweswekile yegazi ngokuphucula impendulo ye-insulin kunye nokunciphisa iglucagon.
3. Ibandakanya iiReceptors zeGlucagon
- Yandisa inkcitho yamandla ngokukhuthaza i-thermogenesis (ukutshiswa kwamafutha).
- Inceda ukususa umzimba ukusuka ekugcinweni kwamafutha ukuya ekusetyenzisweni kwamafutha.
- Ixhasa ukunciphisa ubunzima bexesha elide ngokunyusa izinga le-metabolic.
- Idityanisiwe yeNdlela yokuSebenza kathathu
Ngokujolisa kuzo zontathu ii-receptors, i-Retatrutide ngaxeshanye:
- Ukunciphisa ukutya
- Yandisa ukuhlutha
- Yongeza i-fat metabolism
- Ukuphucula ulawulo lwe-glycemic
Le ndlela ye-triple-hormonal ivumela impembelelo ye-synergistic enamandla ngakumbi kune-GLP-1 okanye i-agonists ezimbini zodwa.
Kuthatha ixesha elingakanani ukubona iziphumo?
Ulingo lwezonyango lubonise iziphumo ezikhawulezayo nezibalulekileyo:
| Ixesha elibekiwe | Iziphumo eziQwalaselweyo |
|---|---|
| Iiveki ezi-4 | Ukunciphisa ukutya, ukuhlutha okuphuculweyo, ukunciphisa ubunzima bokuqala kuqala |
| 8-12 iiveki | Ukulahleka kwamafutha okubonakalayo, ukucutha isinqe esinqeni, ukuphuculwa kwamanqanaba amandla |
| Iinyanga ezi-3-6 | Ukulahleka kwesisindo esibalulekileyo kunye nokuzinza, ukulawula okungcono iswekile yegazi |
| Unyaka om-1 (iiveki ezingama-72) | Ixhomekeke ku24-26% ukunciphisa umzimbakumaqela edosi ephezulu |
Uphuculo lwakwangoko
Uninzi lwabathathi-nxaxheba bachaza ukunyanzeliswa kokutya kunye nokutshintsha kwesisindo sokuqala kwiiveki ze-2-4.
Ukwehla kobunzima obubalulekileyo
Iziphumo eziphambili zibonwa rhoqo kwiinyanga ezi-3, ziqhubekile kwixesha eli-1 lonyaka ngokusetyenziswa okuzinzileyo kunye nedosi efanelekileyo.
Kutheni i-Retatrutide ithathwa njengeNtshukumo
- Ukusebenza kwe-receptors kathathu kuyayihlula kunyango lwangoku.
- Ukusebenza kokwehla kobunzima obuphezulu xa kuthelekiswa ne-GLP-1 okanye iziyobisi ezimbini ze-agonist.
- Ukuphucula impilo ye-metabolic kunye nokwakheka komzimba, ukunciphisa amanqatha ngelixa ugcina izihlunu.
Ukuqukumbela
I-Retatrutide yazisa indlela entsha enamandla yokulawula ubunzima ngokusetyenziswa kweendlela zehomoni zendalo zomzimba. Ngomsebenzi we-agonist kathathu, iyanciphisa umdla wokutya, inyusa imetabolism, kwaye inyusa kakhulu ukulahleka kwamafutha. Nangona ukuphuculwa kwangaphambili kunokubonwa kwinyanga yokuqala, iziphumo eziguqukayo kakhulu zikhula ngokuthe ngcembe kwiinyanga ezininzi-ukwenza i-Retatrutide enye yezona zonyango ezithembisayo zokukhuluphala kunye nezifo ze-metabolic kwixesha elizayo.
Ixesha lokuposa: Oct-28-2025