Yintoni i-mounjaro (iTirzepatide)?

I-Mouutjaro (iTirzepatide) sisiyobisi sokunciphisa umzimba kunye nolondolozo oluqukethe izinto ezisebenzayo zeTirzepatide. I-Tirzpatide yi-gip ezimbini ezinengxaki ye-gip kunye ne-glp-1 iAgonist. Zombini ii-receptors zifumaneka kwi-Pencreatic Alpha kunye ne-Beta Enderrine Cebrine, Intliziyo, imithambo yegazi, ukukhumbula ukhuselo (iLeukocytes), amathumbu kunye nezintso. I-Gip Receptors ifumaneka kwi-adipocyte.
Ukongeza, zombini ii-gip kunye ne-GLP-1 iveliswe kwimimandla yobuchopho ebaluleke kakhulu kummiselo wokutya. I-Tirzpatide inyula kakhulu kwi-GIP yomntu kunye ne-GLP-1 receptors. I-Tirzpatide inezinto ezimbi kakhulu kuzo zombini ii-GIP kunye ne-GLP-1. Umsebenzi weTirzepatide kwii-receptors ze-GIP ziyafana neyo yehomoni yendalo yendalo. Umsebenzi weTirzpatide kwi-GLP-1 Readptors iphantsi kunelo ye-hormone yendalo ye-GLP-1.
I-Mouutjaro (iTirzepatide) isebenza ngokwenza izinto kwingqondo elawula inkanuko, ikwenza uzive ulunge ngakumbi, ulambe, kwaye ungaphantsi kokutya. Oku kuya kukunceda utya kancinci kwaye unciphise umzimba.
I-Mounajaro kufuneka isetyenziswe ngesicwangciso sokutya esincitshisiweyo se-calorie kunye nokwanda komzimba.

Ikhrayitheriya kubandakanya

I-Mouutjaro (iTirzepatide) iboniswe kulawulo lwesisindo, kubandakanya nokuphulukana nobunzima kunye nokugcinwa kwesiqulatho kwi-calorie encitshisiweyo kunye nokwandisa umsebenzi wokutya okuthile kwisalathiso somzimba (i-BMI) ye:
≥ I-30 kg / m2 (i-fede), okanye
≥ 27 kg / m2 ukuya kwi-30 kg / m2 (i-toweight) ene-Dysglycemia (i-Syslipidemia, okanye imvume ye-apneide, okanye imvume yokutya okufanelekileyo
Iminyaka eli-18 -75 yeminyaka
Ukuba isigulana siyasilela ukulahleka okungenani i-5% yobunzima bomzimba wokuqala emva kweenyanga ezi-6, isigqibo kufuneka senziwe ukuba singaqhubeka na unyango, sithathela ingqalelo iprofayili yomngcipheko.

Ishedyuli yedosi

Idosi yokuqala yeTirzeatide yi-2.5 mg kanye ngeveki. Emva kweeveki ezi-4, idosi kufuneka ikhuliswe ibe yi-5 mg kanye ngeveki. Ukuba iyafuneka, idosi inokuthi inyuswe yi-2.5 mg kwiiveki ezi-4 ngaphezulu kwedosi yangoku.
Iidosi zesondlo eziqinisekisiweyo ziyi-5, 10, kunye ne-15 mg.
Idosi ephezulu yi-15 mg kanye ngeveki.

Indlela yokutya

I-Mouutjaro (iTirzepatide) inokulawulwa kanye ngeveki ngalo naliphi na ixesha losuku, kunye okanye ngaphandle kokutya.
Ifanele ifakwe ngokungathamsali esiswini, ithanga, okanye ingalo ephezulu. Indawo yentsholongwane inokutshintshwa. Ayifanelanga ifakwe kakuhle okanye nge-intramcularly.
Ukuba ifuneka, uSuku lweDola leveki lunokutshintshwa logama ixesha eliphakathi kweentsuku ezintathu ubuncinci (> iiyure ezingama-72). Nje ukuba usuku lomdaniso omtsha lukhethiwe, idosi kufuneka iqhubeke ngeveki.
Izigulana kufuneka zicetyiswe ukuba zifunde imiyalelo yokusetyenziswa kwiphakheji ingeniso ngononophelo ngaphambi kokuthatha iyeza.