I-Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH

I-Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OHyitetrapeptide ekhuselweyo eqhele ukusetyenziswa kuphando lwe-peptide synthesis. Amaqela e-Boc (tert-butyloxycarbonyl) kunye ne-tBu (tert-butyl) asebenza njengamaqela akhuselayo ukuthintela ukusabela okusecaleni ngexesha lokudityaniswa kwekhonkco le-peptide. Ukufakwa kwe-Aib (α-aminoisobutyric acid) kunceda ukukhupha izakhiwo ze-helical kunye nokwandisa ukuzinza kwe-peptide. Olu landelelwano lwe-peptide lufundelwa amandla alo kuhlalutyo oluhambelanayo, ukusonga i-peptide, kwaye njengebhloko yokwakha ekuphuhliseni iipeptides ze-bioactive kunye nozinzo oluphuculweyo kunye neenkcukacha.