Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH

Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH

I-Fmoc-L-Lys [Eic (OtBu)-γ-Glu (OtBu)-AEEA-AEEA] -OH yibhloko yokwakha i-amino acid esebenzayo eyenzelwe ukuhanjiswa kweziyobisi ezijoliswe kuyo kunye ne-bioconjugation. Ibonisa i-Eic (eicosanoid) i-moiety yokusebenzisana kwe-lipid, i-γ-Glu yokujolisa, kunye ne-AEEA spacers yokuguquguquka.

 
Uphando & nezicelo:

Isetyenziswe kwi-prodrug synthesis, uphuhliso lwe-ADC, kunye noyilo lwe-nanocarrier

Yandisa ukujoliswa kwe-membrane, ukunyibilika, kunye nokusebenza kakuhle kokudibanisa

Ifanelekile iSPPS kuphando oluphambili lwe-peptide-drug conjugate

Iimpawu zeMveliso (iQela leGentolex):

I-Fmoc ekhuselweyo, ukucoceka okuphezulu (≥99%)

Iqulathe amaqela e-OtBu acandekayo ukwenzela udibaniso olulawulwayo

I-Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH ilungele ukuhanjiswa kweenkqubo ezichanekileyo kunye noyilo olusebenzayo lwepeptide.