Hexarelin

I-Hexarelin API – Isishwankathelo seMveliso

Hexareliniyenziweihomoni yokukhula secretagogue peptide (GHS)kunye namandlaI-GHSR-1a i-agonist, iphuhliselwe ukuvuselelaukukhululwa kwehomoni engapheliyo (GH).. Yeyakheusapho lwe-ghrelin mimetickwaye yenziwe ngama-amino acids amathandathu (i-hexapeptide), enika uzinzo oluphuculweyo lwe-metabolic kunye neziphumo ezinamandla zokukhulula i-GH xa kuthelekiswa ne-analog yangaphambili efana ne-GHRP-6.

IHexarelin ifundwe ngokubanzi kwizicelo zayoi-endocrinology, ukuchithwa kwemisipha, ukulungiswa kwentliziyo, kunye nonyango lokulwa nokuguga, ngenxa yokukwazi ukuphakamisa ngokwemvelo iGH kunyeI-insulin-efana ne-insulin factor 1 (IGF-1)amanqanaba ngaphandle kokwazisa ngokuthe ngqo iihomoni zangaphandle.

Indlela yokwenza

I-Hexarelin ibophelela kwi-ihomoni yokukhula secretagogue receptor (GHSR-1a)kwi-pituitary kunye ne-hypothalamus, ukulinganisa isenzo seghrelin-indlala yendalo yomzimba kunye nehomoni ekhupha iGH.

Iintshukumo eziphambili zefiziyoloji:

• Ivuselela ukukhutshwa kwe-GH ye-pulsatile

• Yandisa ukujikelezaIGF-1amanqanaba

• Iyanyusaiziphumo ze-anabolic(ukukhula kwezihlunu, ukuchacha)

• Ixhasai-fat metabolismkwayeukuvuselelwa kweeseli

• Ngamana umbonisoi-cardioprotectivekwayeanti-apoptoticiziphumo

Ngokungafaniyo nezinye iipeptide zeGHS, iHexarelin iyakwenzaayinyuse kakhulu i-cortisol okanye iprolactin, enikezela ngeprofayili ye-endocrine ecocekileyo.

UPhando kunye nokubanakho kweNyango

1. Ukukhula Kwezihlunu kunye nokuBuyisa

• Iyanyusaubunzima bomzimba obhityileyouphuhliso

• Iyaphuculaukulungiswa kwemisipha kunye nokuvuselelwa

• Wafunda esarcopenia, cachexia, kunye nokubuyisela emva kokuhlinzwa

2. Ukukhuselwa kwentliziyo

• Uphononongo lwangaphambili lubonisaumsebenzi ophuculweyo wentliziyoemva kokulimala kwe-myocardial

• Iyanciphisafibrosis yentliziyokwaye yongezaiqhekeza le-ventricular ejection yasekhohlo

• Ukusetyenziswa okunokwenzeka kwiukumelwa yintliziyokwayeukuguga kwentliziyoiimodeli

3. I-Fat Metabolism & Anti-Aging

• Ukonyukalipolysiskwaye iyaphuculauvakalelo lwe-insulin

• Ixhasaamayeza okulwa nokugugangokusebenzisa i-GH / IGF-1 i-axis stimulation

• Inganceda ukugcinaukuxinana kwamathambo kunye nempilo edibeneyo

Iimpawu ze-API (iQela leGentolex)

• Ubunyulu ≥ 99%

• Iveliswe ngei-soli-phase peptide synthesis (SPPS)

• Imigangatho efana ne-GMP, i-endotoxin ephantsi kunye neentsalela ze-solvent

• Ubonelelo oluguquguqukayo:I-R&D ukuya kwisikali sorhwebo