I-L-Carnitine kukunceda ukuthutha ixesha elide-chain fatty acid yezandla

I-L-Carnitine kukunceda ukuthutha ixesha elide-chain fatty acid amandla amandla

Inkcazo emfutshane:

Inqaku lokunyibilika: "

Ukujikeleza okuthile: -31 (C = 10, H2O)

Inqaku lokubilisa: I-287.5 ° C (uqikelelo oluqhelekileyo)

Ukuxinana: 0.64G / CM3

Isalathiso sokuqaqamba: -32 ° (C = 1, H2O)

Iimeko zokugcina: I-Delobelow + 30 ° C.

I-Solidaity: H2O: 0.1g / Cheacalbolatter20 ° C, Chicing, ayinabala

IFomu: I-CrystalsorcelorTallineponewder

I-Acidity Coanced: (PKA) 3.80 (AT25 ℃)

Umbala: White

Ixabiso le-pH: 6.5-8.5 (50G / L, H2O)

I-Solity yaManzi: 2500G / L (20ºC)

Thumela i-imeyile kuthi

Iinkcukacha zemveliso

Iimpawu zeMveliso

Iinkcukacha zemveliso

Igama	L-carnitine
Inombolo ye-CAS	I-541-15-1
Ifomula yemolekyuli	C7h15no3
Ubunzima bemolekyuli	161.2
Indawo yokunyibilika	Ngo-197-12 ° C
Indawo yokubila	I-287.5 ° C
Ubunyulu	I-99%
Ukugcinwa	Gcina ngezantsi + 30 ° C
Ifom	Umgubo
Umbala	Mhlophe
Ukupakisha	Ibhegi ye-PE + i-aluminium Bag

Izithethantonye

I-carnitine, i-carnnifed (R); I-carning (R); I-Car-Hydroxy)-I-Bhydroxy-the-i-bime-(trimimethymonio) Irhafu;

Isiphumo se-Pharmacociological

Umsebenzi wemigangatho kunye nendima

I-L-Carnitine ikwanesiphumo esithile sokukhuthaza ukusetyenziswa komzimba weKetone kunye ne-nitrogen metabolism.

1. Ukukhuthaza ukuthutha kunye ne-oxidation ye-acids ye-Acids β-oxidation Acids ye-Acids yenziwa kwi-mitochondria yesibindi kunye nezinye iiseli zezicubu. Kuyaziwa ukuba i-acids engaziwayo ingamafutha okanye i-acty acyl-coa inokungena kwi-membrane ye-Innernial, kodwa ke i-acylcarnitine idlula ngokukhawuleza i-membrane yothutho kwi-Acids kwi-Mbrane. Indlela eneenkcukacha zolu thutho ayicacanga, kodwa kuqinisekile ukuba i-Carnitinecyl-Coatransferase (Carnitineacyl-Coatransferase) yi-enzyme ephambili kule nkqubo. Abanye abantu bacinga ukuba i-L-Carnitine inokuthatha inxaxheba kutshololo kunye nokuntywila kwamanye amaqela e-ACYL, oko kungathintela ityhefu ye-acthabolic ebangelwa kukuqokelelwa kwamaqela e-ACKL-CHIAN CHIAN AIID.

2. Ukukhawulezisa i-sperm super kunye nokuphucula ububi l-carnitine yinto yamandla ekufumaneni isidoda, enomsebenzi wokwanda kwesibakala kunye nesondo. Uvavanyo lwamadoda ama-30 amandulo abonisa ukuba inani kunye nobume besidoda zihambelana ngokuthe ngqo kunikezelo lwe-L-Carnitine ekutyeni ngaphakathi kwe-L-Carnitine ngesixhobo se-L-Carnitine ekutyeni.

3. Phucula ukunyamezelana komzimba wattanabet et al. wafumanisa ukuba i-L-Carnitine inokuphucula ukunganyamezeli izigulana ezinezifo ngexesha lokuzivocavoca, i-oxcgen ye-oxygen ye-oxygen, i-oxcgen ye-oxygen emzimbeni, kuya kubakho iidigri ezahlukeneyo; I-Oral L-Carnitine ikwandisa ukunyamezelana kwemisipha ngexesha lokufakwa kwe-oxygen ephezulu ngama-80%, kufihla ixesha lokubuyisa emva kokuzivocavoca, kwaye ukunciphisa uxinzelelo kunye nokudinwa okubangelwa kukuzilolonga. I-Santulli et al. Ifunyenwe ngo-1986 ukuba i-L-Carnitine inokunyusa umgangatho wokukhula kwe-upech ikhule kwaye inciphise umxholo we-cholesterol kunye ne-triglycedide kwizicubu zentlanzi. IJamani yanika ingxelo yokuba emva kokuthatha i-L-Carnitine kwiiveki ezi-3, umxholo wamafutha omzimba wehla kakhulu, kwaye umlinganiso weprotein unyukile, kodwa ubunzima bomzimba abuchaphazeleki.

Ngaphambili: Ukubuyela umva kwi-T3 kwi-synthesis synthesis, umthendeleko, ukuveliswa kwamandla kunye nommiselo

Okulandelayo: I-mecobamin yeyokuphathwa gadalala kweengxaki ze-nerve

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