I-mecobamin yeyokuphathwa gadalala kweengxaki ze-nerve
Iinkcukacha zemveliso
| Igama | Mecobamin |
| Inombolo ye-CAS | 13422-555 |
| Ifomula yemolekyuli | C63h90con13o14p |
| Ubunzima bemolekyuli | 1343.4 |
| Indawo yokunyibilika | > I-190 ° C (Dese.) |
| Ukunyibilikisa | I-DMSO (kancinci), i-methanol (kancinci), amanzi (kancinci) |
| Ubunyulu | I-99% |
| Ukugcinwa | Itywinwe kwi-freezer, engaphantsi kwe-42 ° C |
| Ifom | Uqinile |
| Umbala | Bomvu emnyama |
| Ukupakisha | Ibhegi ye-PE + i-aluminium Bag |
Izithethantonye
I-Mecobamin; Mecobamine; I-Methylcobanbanbaminin; I-Cobamide, i-Chydyl-5,6 ye-Dimyylzbenzimimidamin; I-Vitamin B12; Algobl
Isiphumo se-Pharmacociological
Umsebenzi wemizimba
I-methylcobamin sisiyobisi sokunyanga ukuphazamiseka kwe-nerve. Xa kuthelekiswa nezinye iiNkcazo zeVitamin B12, ithe yazisa okuhle kwizicubu. Inokuphakamisa i-protein-proted-lipid metabolism nge-methyl yokuguqula kwakhona kunye nokulungisa izicubu ze-nerve ezonakalisiweyo. Idlala indima ye-coenazyme kwinkqubo ye-methiinine evela eHomocystene, ngakumbi ithatha inxaxheba kwi-hlersine evela kwi-demoidine evela kwi-DeCeode, kwaye ikhuthaza i-DNA kunye neRNA. Ukongeza, kuvavanyo lweeseli ze-GLIAL, ichiza linyusa umsebenzi we-methionine synthase kwaye ikhuthaza i-synthesis ye-mpin lecimin. Ukuphucula ukuphazamiseka kweMetabolic zezicubu ze-nerus kunokukhuthaza i-axeshes ye-axons kunye neeproteni zazo, yenza isantya sezothutho sezithambisi esisondeleyo kwisiqhelo, kwaye ugcine ukusebenza kwee-axons. Inaliti ye-methylcobbamin inokuthintela ukwenziwa kwe-neracmal tismermermer, ukukhuthaza ukhula kunye neCandelo le-ERYTHROBLSESS, NOKWENZIWAYO I-ANIA. I-methylcobbamin inokukhawuleza ibuyisele i-RED yeseli yeGazi yeGazi, iHomoglobin, kunye neHematocrit ye-rats encitshisiweyo ngenxa yokunqongophala kwe-B12. Isetyenziswe kwi-megaloblastia enemibala ye-megaloblastia kunye ne-Perdiheral Inveres ebangelwa kukungabikho kweVitamin B12.
Isiphumo se-Pharmacociological
I-Methylcobamin yindawo yokukhutshwa kweVitamin B12. Ibizwa ngegama emva kwesakhiwo somchiza. Imele ibizwa ngokuba yi "Methyl Vitamin B12". Inokukhuthaza imetabolism yamafutha, ukukhuthaza i-synthesis yeLecithin kwiiseli ze-Schwann, lungisa i-helin ye-mylin olonakeleyo, kwaye uphucule i-veloction ye-nerve; Ingangenisa ngokuthe ngqo iiseli ze-nerve kwaye ikhuthaze ukuphinda iphinde iphinde ivunjulwe ii-atoon eziphambili; khuthaza iprotein synthesis yeseli ye-nerve, uqinise ngakumbi iAxon Aabolism, nyuse i-Axon Denderation; Thatha inxaxheba kwi-nucleic synthesis, ukukhuthaza umsebenzi we-hematopoie. Ngokwesinyane, idla ngokusetyenziswa kunyango lwe-Diabebethy neuropathy, kwaye ukusetyenziswa kwayo kwexesha elide kunefuthe elithile kwimithambo yegazi enkulu kwiswekile. I-methylcobamin isetyenziselwa ikakhulu kwizifo ze-theipheral ze-peripheral ze-peipheral ezibangelwa sisifo seswekile kunye ne-megaloblastia eneflomia ngenxa yokungabikho kwe-vitamin B12. Isetyenziswe ngokubanzi iklinikhi eneziphumo ebezingalindelekanga ezimbalwa.
Ukusetyenziswa
Isetyenziselwa ukuphatha izifo zentshukumo ye-nervous, ikhulule iintlungu kunye ne-subness, inciphise i-iuralgia, ukuphucula iintlungu ezibangelwa yi-spondvisical spondylosis, kwaye inyathela ngequbuliso, njl njl.
