Pegcetacoplan

Pegcetacoplan API

I-Pegcetacoplan yipeptide ye-pegylated cyclic esebenza njenge-C3 ejoliswe kwi-complement inhibitor, eyenzelwe unyango lwezifo ezincedisayo ezifana ne-paroxysmal nocturnal hemoglobinuria (PNH) kunye ne-geographic atrophy (GA) kwi-macular degeneration ehlobene neminyaka.

Inkqubo kunye noPhando:
I-Pegcetacoplan ibophelela ekuncediseni iprotheni ye-C3 kunye ne-C3b, ikhusela ukusebenza kwe-cascade yokuncedisa. Oku kunciphisa:
I-Hemolysis kunye nokuvuvukala kwi-PNH
Umonakalo weseli ye-retinal kwi-geographic atrophy
Ukulimala kwezicubu ezixhomekeke kwi-immune kwezinye iziphazamiso eziqhutywa ngokuhambelanayo