I-ru-58841 isetyenziswe njengokuthintela ilahleko yeencazelo kunye nepatheni yepateni yendoda
Iinkcukacha zemveliso
| Igama | Ru-58841 |
| Inombolo ye-CAS | 154992-24-24-2 |
| Ifomula yemolekyuli | C17h18f3N3O3O |
| Ubunzima bemolekyuli | 369.34 |
| Inombolo ye-einecs | I-159273-453-0-0-0 |
| Indawo yokubila | 493.6 ± 55.0 ° C (iqikelelwe) |
| Ukuxinana | 1.39 |
| Imeko yokugcina | Itywinwe kwi-freezer, engaphantsi kwe-42 ° C |
| Ifom | Umgubo |
| Umbala | Mhlophe |
| Ukupakisha | Ibhegi ye-PE + i-aluminium Bag |
Izithethantonye
R58441; 4- (4,4-Dimyeyyl-2,5-Dooxo-3- I-Nitrrile; 4- [3- I-deitrile; 4- [3- I-ZonittRile; ru-58841e: I-Candyli (kwi-Spire) ye-CORGEARNARSEMA; CS-637; ru58841; ru5841; ru-58841
Isiphumo se-Pharmacociological
Inkcazo
Ru 58841 (I-PSK-3841) yi-Androgen Receptor anti ikhuthaza iinwele zikhulisa iinwele.I-RU58841 sisiyobisi esiphandeni esidalwe kunyango ngokuchasene ne-Androgenic Alopecia, ekwabizwa ngokuba yi-Baldness yendoda (MPD).
Njenge-Anti-Androgen ye-Androgen, imigaqo-nkqubo yayo yesenzo ayifani ne-Fibiterde. I-Fibiastetide isebenza ngokuthe ngqo kwi-5cy Reftatase, intembelela ukuguqulwa kweTestosterone kwi-DHT, kwaye inciphise umxholo we-DHT emzimbeni. I-RU58841 iBhola phakathi kweDihydrotestosterone kunye nee-Follictors ze-ficloule, aziyinciphisi ngqo umxholo we-DHT, kodwa inciphisa ukubopha ii-DHT kunye ne-finnet ye-DARTECINGNATIC.
4- (3- (4-Hydroxybybyl) -4,4-Dimyethyl-2,5-DiOXO-1Ukuba 4- [3- (4-Hydroxybuyl) -4,4-Dimthyl-2,5-I-Dioxo-1-ImelalaromethylKwimeko yokudibana kwesikhumba, susa iimpahla ezingcolisekileyo, ulusu olungcolisekileyo ngesepha namanzi, kwaye ufune ingqalelo yonyango ukuba ukungonwabi kwenzeka;
Imiphumela
I-RU58841 isetyenziselwa isikali, ingene kwiifoto zeenwele, kunye nethiyori, inokungena egazini kwaye ichaphazele amanye amalungu omzimba. Kodwa akukho ziphumo ebezingalindelekanga zenkqubo ifunyenwe kwizifundo zesicelo se-prokes. Nangona kunjalo, abanye abantu abaye bazama ibango le-ru58441 babone iziphumo ebezingalindelekanga ezivela ekusebenziseni i-ru, kubandakanya ukucaphuka kwesikhumba, ukuncipha kwe-lirerile, i-eredile, ukungasebenzi kakuhle, isiyethe, kunye nentloko.
