I-Triamterene ikakhulu kunyango lwezifo ze-Edematous
Iinkcukacha zemveliso
| Igama | Triamterene |
| Inombolo ye-CAS | 396-01-0-0 |
| Ifomula yemolekyuli | C11h11n7 |
| Ubunzima bemolekyuli | 253.26 |
| Inombolo ye-einecs | 206-904-3 |
| Indawo yokubila | I-386.46 ° C |
| Ubunyulu | I-98% |
| Ukugcinwa | Itywinwe kubushushu bomileyo, igumbi |
| Ifom | Umgubo |
| Umbala | Ityheli ityheli |
| Ukupakisha | Ibhegi ye-PE + i-aluminium Bag |
Izithethantonye
I-6-phenyl-; I-7-ppridinethamine, 6-phenyl-4; i-ditak; i-dyren; i-dyrenium; i-dytac
Isiphumo se-Pharmacociological
Amagqabantshintshi
I-Triamterene sisiseko se-potassium-i-suresitic, enefuthe lokugcina i-potalium kunye ne-sodium ekhuthazayo ifana ne-spironolactone, kodwa indlela yesenzo yahlukile. Isenesiphumo se-noureitic emva kokuthintela ukufihlwa kwe-Aldesterone nge-sodium chloride okanye isusa i-adrenal gland. Indawo yayo yesenzo ikwi-cubule ye-distal ye-dirule, ithintele ukutshintshiselana nge-sodium kunye ne-potassium zesodium kunye ne-potassium, i-potassium ze-ions, ukunyusa ukungavisisani kwe-NA + kunye nochazo, kunye nokunciphisa ukungavisisani kwe-k +. Ingathintela kwakhona ukuphindaphinda kwe-NA + kunye nokugcinwa kwe-K + ngokuqokelela i-duct. Iziphumo ze-noureiting zale mveliso zibuthathaka. Xa isetyenziswa ngokudibeneyo ne-thritics enjenge-thuaiazide, ayinakukomeleza kuphela isiphumo sokulandelelaka kunye ne-moureitic yeyokugqibela, kodwa ikwanciphise ukuphendula okungalunganga kwe-potassium. Ukongeza, kukho nesiphumo sempembelelo ye-acid ekhuthazayo. Ukusetyenziswa kwexesha elide kunokunyusa amanqanaba egazi u-Urea. Isetyenziselwa ikakhulu kwi-Edema engacacanga okanye i-ascates ebangelwa kukusilela kwentliziyo, i-Parritisis yesiqhelo kunye ne-piphritis engapheliyo. Ingasetyenziselwa izigulana ezingasebenziyo kunye ne-hydrochlorochiazide okanye i-spironolactorne.
Isiphumo se-Pharmacociological
Le mveliso yindawo yokugcina i-potangaum-i-ouretic, ethintela ngokuthe ngqo i-Na + -K + itshintshiselana phakathi kwe-Na +, ikhulisa ukungcola kwezintso,, kunye namanzi, ngelixa kuncitshiswa ukungavisisani kwe-k +.
Iphawu
Isetyenziselwa ikakhulu kunyango lwezifo ze-Edema; kubandakanya ukungaphumeleli kwentliziyo, isibindi se-Prithois Ascites, i-Nephrotic syndrome kunye ne-Sydium yokugcina ngexesha lokunyanga kwe-adrenalticoids; Ingasetyenziselwa impatho ye-idiopathic Edema.
Ukusetyenziswa
Ingcongconi ebuthathaka. Impembelelo ngokukhawuleza kwaye i-Duresis iqala iiyure ezi-2 emva kolawulo lomlomo, ifikelela kwi-piak kwiiyure ezi-6, kwaye ifuthe lihlala iiyure eziyi-8 ukuya kwezi-12. Isetyenziselwa iKlinikhi ye-Edema engacacanga okanye i-asctes ebangelwa kukusilela kwentliziyo, iPricthoisis yesifo kunye nePhistis engapheliyo, kwaye ikwasetyenziselwa i-hydrochlorochiazide okanye i-spironolactone. amatyala. Le mveliso inomsebenzi wokuphelisa i-acid i-iric kwaye ilungele ukuphathwa kwe-gout.
