I-Desmopressin Acetate yokuNyanga i-Diabetes Insipidus ephakathi
Iinkcukacha zeMveliso
| Igama | I-Desmopressin |
| Inombolo yeCAS | 16679-58-6 |
| Ifomula yemolekyuli | I-C46H64N14O12S2 |
| Ubunzima bemolekyuli | 1069.22 |
| Inombolo ye-EINECS | 240-726-7 |
| Ukujikeleza okuthe ngqo | D25 +85.5 ± 2 ° (ibalwe kwipeptide yasimahla) |
| Ukuxinana | 1.56±0.1 g/cm3(Kuxelwe kwangaphambili) |
| Inombolo ye-RTECS | YW9000000 |
| Iimeko zokugcina | Gcina ku-0°C |
| Ukunyibilika | I-H2O: i-soluble20mg/mL, icacile, ayinambala |
| I-acidity coefficient | (pKa) 9.90±0.15 (Kuxelwe kwangaphambili) |
Izithethantonye
I-MPR-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2; I-MINIRIN; [DEAMINO1, DARG8] VASOPRESSIN; [DEAMINO-CYS1, D-ARG8]-VASOPRESSIN; I-DDAVP, UMNTU; I-DESMOPRESSIN; UDESMOPRESSIN, UMNTU; DESAMINO-[D-ARG8] VASOPRESSIN
Iimpawu
(1) Unyango lwe-diabetes insipidus ephakathi. Emva kokuba ichiza linokunciphisa ukukhutshwa komchamo, ukunciphisa ukuphindaphinda komchamo kunye nokunciphisa i-nocturia.
(2) Unyango lwe-enuresis yasebusuku (izigulane ezineminyaka eyi-5 okanye ngaphezulu).
(3) Vavanya umsebenzi wokuxinanisa umchamo wezintso, kwaye uqhube ukuxilongwa ngokuhlukileyo komsebenzi wezintso.
(4) Kwi-hemophilia kunye nezinye izifo ezophayo, le mveliso inokunciphisa ixesha lokuphuma kwegazi kwaye ithintele ukopha. Inokunciphisa inani lokulahleka kwegazi kwi-intraoperative kunye ne-postoperative oozing; ngakumbi ngokubambisana noxinzelelo lwegazi olulawulwa ngokufanelekileyo ngexesha lotyando, kunokunciphisa ukuphuma kwegazi kwi-intraoperative kwiindlela ezahlukeneyo, kunye nokunciphisa i-postoperative, enokuthi idlale indima engcono ekukhuseleni igazi.
Unyango lwe-diabetes insipidus
Isifo seswekile insipidus ikakhulu sisifo semetabolism yamanzi ebonakaliswa ngumchamo omninzi, i-polydipsia, i-hypoosmolarity, kunye ne-hypernatremia. Ukunqongophala okukodwa okanye okupheleleyo kwe-vasopressin (i-central diabetes insipidus), okanye ukungaphumeleli kwezintso ze-vasopressin (i-nephrogenic diabetes insipidus) inokuqala. Ngokweklinikhi, i-diabetes insipidus ifana ne-polydipsia ephambili, imeko apho ukugqithiswa kwamanzi amaninzi kubangelwa ukungasebenzi kakuhle kwendlela yokulawula okanye ukoma okungaqhelekanga. Ngokuchasene ne-polydipsia ephambili, ukunyuka kwamanzi kwizigulane ezine-diabetes insipidus yimpendulo ehambelanayo neenguqu kwixinzelelo lwe-osmotic okanye umthamo wegazi.
