I-Ganirelix Acetate API

Inkcazo emfutshane:

Igama: I-Ganirelix Acetate

Inombolo ye-CAS: 123246-29-7-7

Ifomula yemolekyula: c80h113cln18O13O

Ubunzima bemolekyuli: 1570.34

Thumela i-imeyile kuthi

Iinkcukacha zemveliso

Iimpawu zeMveliso

Iinkcukacha zemveliso

Igama	I-Ganirelix Acetate
Inombolo ye-CAS	123246-29-7-7-7
Ifomula yemolekyuli	C80h113cln18O13O
Ubunzima bemolekyuli	I-1570.34

Izithethantonye

I-AC-DNAL-DCPA-DCPA-DPPAL-SERR-DHAR-DHAR (ET2) -U-HETE-HALA-DALA-HALA-HINHIXOM; I-Ganielix; Ganirelix; I-Ganirelix Acetate USP / EP /

Inkcazo

I-Ganirelix yindawo yediski yokutyumba, kunye netyuwa yayo ye-acetate, i-ganirelix i-gonadretropin-ukukhulula i-hormone (GNRH) i-Adagonist. Ulandelelwano lwe-Amino Alid yi: I-Ac-D-D-2NAL-D-D-D-D-T-T-D-ET-L-L-I-ET-L-L-I-ET-L-NH-HOORGE (9,10-I-ET2)-DH2. Kuyintloko ikakhulu, isetyenziswa kubafazi abasebenza kwitekhnoloji yokubonelela ngovuselelo lwe-ovarian yokuhambisa i-ovarian ukuthintela i-hormone ye-hormone ye-hormone kunye nokunyanga ukuphazamiseka ngenxa yesi sizathu. Iyeza ichiza lineempawu zokuphendula ezingalunganga, ireyithi yokukhulelwa ephakamileyo kunye nexesha elifutshane lonyango, kwaye linenzuzo ebonakalayo xa kuthelekiswa namachiza afanayo kwikhondo lekliniki.

Inketho ye-Pharmacological

Ukukhutshwa kwe-pulsatile ye-gonadropin-ukukhulula i-hormone (i-vrh) ivuselela i-synthes kunye nokugcinwa kwe-LH kunye ne-fsh. I-frequency ye-lh ijula phakathi kunye nezigaba ze-ofliclar ezifihlakeleyo zimalunga ne-1 ngeyure. Ezi pulses zibonakaliswa kwixesha elifanelekileyo ziphakama kwi-serum lh. Ngexesha le-goartriali, ukukhutshwa okukhulu kwe-gnrh kubangela ukuphepha i-LH. I-Midmerboardrual Lh therge inokuphanga iimpendulo ezininzi zembonakalo, kubandakanya: i-ovulation, i-Oocyte Metiotic, kunye ne-Corpus Lutetic. Ukuqulunqwa kwe-Corpus Lutum kubangela ukuba amanqanaba e-serum ahlukanisa, ngelixa amanqanaba e-Estradiol awele. I-Ganirelix Acetate yi-antigonist ekhuphisanayo ekhuphisanayo kwiibhloko ze-GNRH kwi-gonadotrophs kunye neendlela ezilandelayo. Ivelisa isithintelo esikhawulezayo, esibuyiselweyo se-gonadropin. Isiphumo sokuthintela i-genirelix ye-genirelix kwi-pituitary lh yayinamandla ngakumbi kunoko. I-Ganirelix Acetate ayiphumelelanga ukukhutshwa kokuqala kwe-Endogenolopins ye-Endogenolotus, iyahambelana nokuchasa. Ukubuyiselwa kwakhona kwe-pituitary lh kunye namanqanaba e-FSH kwenzeka kwiiyure ezingama-48 emva kokuba i-ganirelix ye-Ganicelix yayekisiwe.

Ngaphambili: I-Cetrorelix ye-Acetate ukuthintela i-ovulation ye-120287-85-6

Okulandelayo: I-Linkeclolololololotide ye-Gastrointenal Distles 85119-599-5-2

Bhala umyalezo apha kwaye uthumele kuthi