Ipamorelin

Ipamorelin API

I-Ipamorelin yi-hormone yokukhula ye-pentapeptide ekhupha i-peptide (GHRP) eyenziwe ngama-amino acids amahlanu (Aib-His-D-2-Nal-D-Phe-Lys-NH₂). I-agonist ekhethiweyo ye-GHSR-1a enekhono lokuvuselela i-hormone yokukhula (GH) eyimfihlo kunye neenkcukacha eziphezulu. Xa kuthelekiswa nee-GHRP zangaphambili (ezifana ne-GHRP-2 kunye ne-GHRP-6), i-Ipamorelin ibonisa ukukhetha okungcono, ukhuseleko kunye nokuzinza kwe-pharmacological ngaphandle kokuchaphazela kakhulu amanqanaba amanye amahomoni afana ne-cortisol, i-prolactin okanye i-ACTH.

Njenge-API ye-peptide ebonwa kakhulu, i-Ipamorelin okwangoku isetyenziswa ngokubanzi kuphando oluchasayo, ukuvuselelwa kwezemidlalo, ukungenelela kwe-osteoporosis, ukubuyisela emva kokusebenza kunye nokulawulwa komsebenzi we-metabolic.

UPhando kunye neNdlela yokuSebenza

I-Ipamorelin ikhuthaza ukukhululwa kwe-hormone yokukhula engapheliyo (GH) kwi-pituitary yangaphambili ngokukhetha ngokukhetha i-hormone yokukhula i-secretion receptor (GHSR-1a) kunye nokulinganisa isenzo se-ghrelin. Iindlela zayo eziphambili ze-pharmacological ziquka:
1. Ukuvuselela i-GH secretion
I-Ipamorelin ikhetha kakhulu i-GHSR-1a, ibangela ukuba i-pituitary gland ikhulule i-GH ngaphandle kokuchaphazela kakhulu i-ACTH okanye amanqanaba e-cortisol, kwaye inokhuseleko olungcono lwe-endocrine.
2. Ukuphucula iprotheni synthesis kunye nokulungiswa kweeseli
Ngokunyusa amanqanaba e-IGF-1, ikhuthaza i-anabolism ye-muscle ye-muscle, iphucula ukulungiswa kwezicubu kunye nokuvuselelwa, kwaye ifanelekile ukulungiswa kwe-trauma, ukubuyiswa kokuhlinzwa kunye nonyango lwe-anti-muscle atrophy.
3. Ukuphucula imetabolism kunye nokusabalalisa kwamafutha
I-GH ineempembelelo zokuhlanganiswa kwamafutha kunye nokuphuculwa kwe-insulin. I-Ipamorelin inokuncedisa ekulawuleni isimo se-metabolic kwaye isetyenziselwa uphando kwi-syndrome ye-metabolic kunye nokungenelela kokukhuluphala.
4. Ukuphucula ukuxinana kwamathambo kunye nokuchasana nokuguga
I-GH / IGF-1 i-axis inokukhuthaza ukubunjwa kwamathambo kunye ne-mineralization. I-Ipamorelin ibonisa isithembiso kwi-anti-osteoporosis, ukulungiswa kwe-fracture kunye nokuchasana nokuguga.
5. Phucula isigqi se-circadian kunye nomgangatho wokulala
Ukukhutshwa kwe-GH ngokuqhelekileyo kuhamba kunye nobuthongo obunzulu. Izifundo ziye zafumanisa ukuba i-Ipamorelin inokuphucula ngokungathanga ngqo isakhiwo sokulala kunye nokuphucula amandla okubuyisela umzimba.
Izifundo zangaphambi kweklinikhi kunye nokuqinisekisa ukusebenza kakuhle

Nangona kusekho kwinqanaba lokuqala leklinikhi, i-Ipamorelin ibonise ukhuseleko oluhle kunye nokusebenza kakuhle kwizilwanyana kunye nezinye izifundo zabantu:

Amanqanaba e-GH anyuswa kakhulu (incopho ngaphakathi kwemizuzu engama-30, ihlala iiyure ezininzi)

Akukho nto icacileyo yepro-cortisol okanye i-pro-ACTH isiphumo, iziphumo ze-endocrine zilawuleka ngakumbi

Phucula ubunzima bemisipha kunye namandla (ingakumbi kwiimodeli zezilwanyana ezindala)

Ukuphucula ukubuyisela emva kokuhlinzwa kunye nesantya sokulungiswa kwezicubu

Ukunyuka kwamanqanaba e-IGF-1 kunceda ukulungiswa kweeseli kunye nokuphendula kwe-antioxidant

Ukongezelela, i-Ipamorelin idibene nezinye iimimetics ze-GHRH (ezifana ne-CJC-1295) kwezinye izifundo zibonise imiphumo ye-synergistic, iqhubekisela phambili ukukhululwa kwe-pulse ye-GH.
Ukuveliswa kwe-API kunye nokuqinisekiswa komgangatho

I-Ipamorelin API enikezelwa yiGentolex Group yethu ilungiselelwe ngokusebenzisa umgangatho ophezulu ** inkqubo ye-peptide synthesis yesigaba esiqinileyo (SPPS) **, kwaye ihlanjululwe ngokungqongqo kwaye ihlolwe umgangatho, ifanelekile kuphando lwezenzululwazi kunye nophuhliso kunye nokusetyenziswa kwemibhobho yokuqala yeenkampani zonyango.

Iimpawu zemveliso ziquka:

Ubunyulu ≥99% (uvavanyo lweHPLC)
Ayikho i-endotoxin, i-solvent eshiyekileyo ephantsi, ukungcoliseka kwe-ion yentsimbi
Ukubonelela ngesethi epheleleyo yamaxwebhu asemgangathweni: i-COA, ingxelo yokufunda ukuzinza, uhlalutyo lwe-spectrum yokungcola, njl.
Customizable gram-level ~ kilogram-level unikezelo