I-Micafungin ye-antifungal kunye ne-antiviral
Iinkcukacha zeMveliso
| Igama | Micafungin |
| Inombolo yeCAS | 235114-32-6 |
| Ifomula yemolekyuli | I-C56H71N9O23S |
| Ubunzima bemolekyuli | 1270.28 |
| Inombolo ye-EINECS | 1806241-263-5 |
I-Clinical Pharmacology
Le mveliso yeyokufakwa kwi-intravenous. I-concentration ye-plasma ifikelela kwinqanaba eliphezulu ekupheleni kokunyuswa, kwaye ukuphelisa isiqingatha-ubomi ziiyure eziyi-13.9. Ukuxinwa kwe-micafungin kwimiphunga, isibindi, i-spleen kunye nezicubu zezintso yeyona iphakamileyo, kodwa ayibonakali kwi-cerebrospinal fluid. Emva kokufakwa kwi-intravenous, i-metabolized ikakhulu esibindini kwaye ikhutshwe kwindle kunye nomchamo.
Umsebenzi
I-dose ephakanyisiweyo yonyango lwe-candidiasis ye-esophageal yi-150 mg ngosuku, kunye ne-dose ephakanyisiweyo yokuthintela usulelo lwe-Candida kwizigulane ze-hematopoietic stem cell transplant yi-50 mg ngosuku. Ngokutsho kwedatha yeklinikhi ekhoyo, umyinge wonyango okanye uthintelo lwezifo ezibini ezingentla ziyi-15 iintsuku kunye neentsuku ze-19, ngokulandelanayo. Iyeza lilungiswe kwaye lihlanjululwe nge-saline eqhelekileyo okanye i-5% ye-dextrose injection. Ixesha lokulawula kufuneka libe ubuncinane iyure eli-1, ngaphandle koko kulula ukuvelisa ukusabela okubi.
Ukunxibelelana kwezamayeza
Incopho yoxinaniso lwe-plasma ye-nifedipine inokunyuswa ngama-42%, kwaye ukuba kuyimfuneko, cinga ukunciphisa umthamo we-nifedipine okanye ukuyeka ichiza. Ummandla ophantsi kwejiko lokuxinana kweplasma yechiza elichasayo iSirolimus lonyuke nge-21%, kwaye ukuncitshiswa kwethamo le-sirolimus kufuneka kuthathelwe ingqalelo njengento efanelekileyo. Amachiza e-Antifungal, i-pharmacology yeklinikhi, ukusetyenziswa, ukusabela okubi, njl njl. ye-micafungin
FAQ
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