Motixafortide

Motixafortide API

I-Motixafortide yi-peptide yokwenziwa kwe-CXCR4 echasene ne-peptide ephuhliswe ukudibanisa iiseli ze-hematopoietic stem (HSCs) ukwenzela ukutshintshwa kwe-autologous kwaye iphinda ifundwe kwi-oncology kunye ne-immunotherapy.

Inkqubo kunye noPhando:

I-Motixafortide ivimba i-CXCR4-SDF-1 axis, ekhokelela ku:
Ukuhlanganiswa kweeseli ze-stem ngokukhawuleza kwigazi le-peripheral
Ukuthengiswa kweeseli ze-immune kunye nokungena kwe-tumor
I-synergy enokwenzeka kunye ne-checkpoint inhibitors kunye ne-chemotherapy

Ibonise isivuno esiphezulu se-stem cell xa kuthelekiswa nabaququzeleli abakhoyo kwiimvavanyo zeklinikhi.
Iimpawu ze-API (iQela leGentolex):

I-peptide yokwenziwa ecocekileyo ephezulu
Imigangatho yemveliso efana ne-GMP
Ifanelekile kwimixube etofwayo

I-Motixafortide API ixhasa uphando oluphambili kunyango lwe-stem cell kunye ne-cancer immunotherapy.