I-Atosiban Acetate isetyenziselwe ukuzalwa ngaphambi kwexesha
Iinkcukacha zemveliso
| Igama | Atosiban |
| Inombolo ye-CAS | I-90779-69-4-4-4 |
| Ifomula yemolekyuli | C43h67N12S2s2 |
| Ubunzima bemolekyuli | 994.19 |
| Inombolo ye-einecs | 806-815-5 |
| Indawo yokubila | I-1469.0 ± 65.0 ° C (iqikelelwe) |
| Ukuxinana | 1.254 ± 0.06 g / cm3 (eqikelelweyo) |
| Iimeko zokugcina | -2 ° C |
| Ukunyibilikisa | H2o: ≤100 mg / ml |
Inkcazo
I-Atosiban I-Acetate yi-discheclide ye-PolypePide equka i-9 Amino Acids. Yimolekyuli ye-oxytocin eguqulweyo kwizikhundla 1, 2, 4 ne-8. I-N-theminus ye-Peptide yi-Acid (i-C-tercal kunye ne-Amino Acid ye-Aminal, i-I-Amino Acid ye-N-terlisile iguqulwe .
Isicelo
I-Atosiban yi-Oxytocin kunye ne-vaspresn v1i edibeneyo, i-Oxytocin Caceptor iyafana ne-vaspresn v1a ye-vasprector. Xa i-Caceptoctor ye-Oxetocin ivaliwe, i-oxytocin isenokwenza into nge-V1A ye-V1A, ke iyimfuneko ukuthintela iindlela ezimbini ze-Readptors ngexesha elinye, kwaye inkokeli enye ye-interine ithintele i-subrine. Esi sesinye sezizathu eziphambili zokuba i-β-iarpor, i-calcium Channers i-blockers kunye ne-prostaglanan ye-synthase infinitors ayinakuthintela ukuqiniseka nge-iTrine.
Isiphumo
I-Atosiban i-Anppring Asvatorist ye-oxytocin kunye ne-vaskopresn v1a, inkqubo yekhemikhali ifana ne-Oxkota kunye ne-vaspresn v1a ye-Ox Tytocin kunye ne-vaspressin v1a, i-vaskopresn kunye nokunciphisa ikhontrakthi ye-vaspresn kunye nokunciphisa ikhontrakthi ye-vaspresn kunye nokunciphisa ikhontrakthi ye-vaspresn.
