Pharma APIs
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Fmoc-Yakhe-Aib-OH
I-Fmoc-His-Aib-OH yibhloko yokwakha yeepeptide esetyenziswa kwi-peptide synthesis, edibanisa i-Fmoc-protected histidine kunye ne-Aib (α-aminoisobutyric acid). I-Aib yazisa ukuqina kwe-conformational, iyenza ixabiseke ekuyileni i-helical kunye ne-stable peptides.
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Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
I-Boc-His (Trt)-Aib-Glu (OtBu)-Gly-OH isiqwenga se-tetrapeptide ekhuselweyo esisetyenziswe kwi-peptide synthesis kunye nophuhliso lweziyobisi. Iqulethe amaqela asebenzayo akhuselweyo ngobuchule bokudibanisa i-stepwise kunye neempawu ze-Aib (α-aminoisobutyric acid) ukunyusa uzinzo lwe-helix kunye nobulukhuni be-conformational.
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Ste-γ-Glu-AEEA-AEEA-OSU
I-Ste-γ-Glu-AEEA-AEEA-OSU yi-synthetic lipidated linker molecule eyenzelwe ukuhanjiswa kwechiza ekujoliswe kulo kunye ne-antibody-drug conjugates (ADCs). Ibonisa umsila we-stearoyl (Ste) we-hydrophobic, i-γ-glutamyl ejoliswe kuyo, i-AEEA spacers yokuguquguquka, kunye neqela le-OSu (NHS ester) lokudibanisa ngokufanelekileyo.
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Fmoc-Ile-αMeLeu-Leu-OH
I-Fmoc-Ile-αMeLeu-Leu-OH yibhloko yokwakha ekhuselweyo ye-tripeptide ene-α-methylated leucine, esetyenziswa ngokuqhelekileyo kwi-peptide yoyilo lweziyobisi ukuphucula ukuzinza kwe-metabolic kunye nokukhetha kwe-receptor.
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I-Dodecyl Phosphocholine (DPC)
I-Dodecyl Phosphocholine (DPC) sisicoci sokwenziwa se-zwitterionic esisetyenziswa kakhulu kuphando lweprotheyini yenwebu kunye nebhayoloji yolwakhiwo, ngakumbi kwi-NMR spectroscopy kunye necrystallography.
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I-Caspofungin ye-Antifungal Infections
Igama: Caspofungin
Inombolo ye-CAS: 162808-62-0
Ifomula yemolekyuli: C52H88N10O15
Ubunzima bemolekyuli: 1093.31
Inombolo ye-EINECS: 1806241-263-5
Indawo yokubilisa: 1408.1±65.0 °C (Kuqikelelwe)
Ubuninzi: 1.36±0.1 g/cm3(Kuqikelelwe)
I-Acidity coefficient: (pKa) 9.86±0.26 (Kuqikelelwe)
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I-Daptomycin 103060-53-3 yeZifo ezosulelayo
Igama: Daptomycin
Inombolo ye-CAS: 103060-53-3
Ifomula yemolekyuli: C72H101N17O26
Ubunzima bemolekyuli: 1620.67
Inombolo ye-EINECS: 600-389-2
Indawo yokunyibilika: 202-204°C
Indawo yokubila: 2078.2±65.0 °C (Kuqikelelwe)
Ubuninzi: 1.45±0.1 g/cm3(Kuqikelelwe)
Indawo edanyazayo: 87℃
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I-Micafungin ye-antifungal kunye ne-antiviral
Igama: Micafungin
Inombolo ye-CAS: 235114-32-6
Ifomula yemolekyuli: C56H71N9O23S
Ubunzima bemolekyuli: 1270.28
Inombolo ye-EINECS: 1806241-263-5
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IVancomycin sisithinteli-ntsholongwane se-glycopeptide esisetyenziselwa i-antibacterial
Igama: Vancomycin
Inombolo ye-CAS: 1404-90-6
Ifomula yemolekyuli: C66H75Cl2N9O24
Ubunzima bemolekyuli: 1449.25
Inombolo ye-EINECS: 215-772-6
Ubuninzi: 1.2882 (uqikelelo olurhabaxa)
Isalathiso se-refractive: 1.7350 (uqikelelo)
Iimeko zogcino: Ivalwe kwindawo eyomileyo, 2-8°C
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I-Vardenafil Dihydrochloride Ukunyanga i-Erectile Dysfunction 224785-91-5
Inombolo ye-CAS: 224785-91-5
Ifomula yemolekyuli: C23H32N6O4S
Ubunzima bemolekyuli: 488.6
Inombolo ye-EINECS: 607-088-5
Indawo yokunyibilika: 230-235°C
Ubuninzi: 1.37
Indawo edanyazayo: 9℃
Iimeko zokugcina: Ivalwe kwindawo eyomileyo, Gcina kwisikhenkcisi, ngaphantsi kwe -20°C
I-acidity coefficient: (pKa) 9.86±0.20 (Kuqikelelwe)
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I-Orlistat 96829-58-2 Ukunciphisa i-Absorption ye-Sietary Fat, okukhokelela ekulahlekeni kobunzima
Inombolo ye-CAS: 96829-58-2
Ifomula yemolekyuli: C29H53NO5
Ubunzima bemolekyuli: 495.73
Inombolo ye-EINECS: 639-755-1
Ukujikeleza okuthe ngqo: D20-32.0°(c=1inchloroform)
Indawo yokubila: 615.9±30.0°C (Kuqikelelwe)
Ubuninzi: 0.976±0.06g/cm3(Kuxelwe kwangaphambili)
Iimeko zokugcina: 2-8°C
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I-RU-58841 Isetyenziswe njengoThintelo lokulahleka kweNwele kunye neMpatheni yobudoda
Inombolo ye-CB: CB51396657
Igama: RU 58841
Inombolo ye-CAS: 154992-24-2
Ifomula yemolekyuli: C17H18F3N3O3
Ubunzima bemolekyuli: 369.34
Inombolo ye-EINECS: 1592732-453-0