I-Linkeclolololololotide ye-Gastrointenal Distles 85119-599-5-2
Iinkcukacha zemveliso
| Igama | I-LinkeclololololoLotide |
| Inombolo ye-CAS | I-851199-592-2 |
| Ifomula yemolekyuli | C59h79n15O21Os6 |
| Ubunzima bemolekyuli | 1526.74 |
Izithethantonye
Linacllotide;Linaclotide;LinaelotideAcetate;Linaelotide;CY-14;Liclotide;Argpessin;L-Tyrosine,L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl -K-l-l-l-l-l-l-l-l-l-l-l-l-l-alanyl-l-csteinyl-l-i-→steinyl-l
Inkcazo
I-Linkeclolololololololotide, isakhiwo sePeptEide esinee-Amino Acid, sihambelana ne-Endobernous Guanosine New Guider kwaye kuphela i-FDA-C ivunyiwe i-curclase-c) kunye nokuqunjelwa kwe-idiopathic kunyango (i-iCIC) kubantu abadala.
Iipropathi zeekhemikhali
I-LinAclolololololotide i-white ukuya kwi-amorphous ye-amorphous emhlophe; Inyibilikihla kancinci emanzini kunye ne-aceus sodium chloride (i-0.9%).
Ingaba isebenza kanjani
I-LinAclololololotide yi-Guany Cyplase-C Reclorter Agonist (GCCA) kunye nomsebenzi we-visceral and on. Zombini i-Lidaclololololololotide kunye neMetabolite yayo zinokubopha kwiGuanhlase-C (GC-C) kumhlaba we-leminal opinellium omncinci. Kwimodeli yezilwanyana, i-ligama ye-Linaclolotide inciphisa iintlungu ze-visceral kwaye yonyusa ukuhamba kwe-gestrointenal ngokuvula i-GC-C, kwaye ebantwini, ichiza likwandisa ibala. Iziphumo zokusetyenziswa kwe-GC-C inyuswe i-geracellillar kunye ne-overcellir cg I-CGMPM ye-Overcelliary inokunciphisa umsebenzi weentsinga ze-nerve zentlungu kwaye zinciphise iintlungu ze-visceral kwizilwanyana ezimodeli. I-CGraceLlar CGMPO ingenyusa imfihlo ye-chloride kunye ne-bicarbonate kwithumbu elincinci ngokusebenzisa i-CFTR (ekhokelela ekunyukeni kwamathumbu amathumbu kunye nesantya sokuhamba kwamathumbu amancinci.
FAQ
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